Tuesday, February 10, 2015

Toxin Tuesdays: Xylitol

With no antidote available, aggressive treatment is required (image source)
Xylitol is a sweetener found in many human products. While sweet to humans, it can be deadly to our pets. Most exposures come from sugar free gum that our pets have found and ingested, however, xylitol is becoming very popular and can be found in many backing products, candies and even toothpaste. If your dog has had exposure to these products it is important to take action immediately!
 
There are MANY different sources of Xylitol found around the home (Image Source)
Why is Xylitol such a serious problem for our pets? One of the biggest problems is that Xylitol is very easily and rapidly digested. This means once your pet eats it, it will be very difficult to get it back. The first obstacle that we have to deal with is that Xylitol can lead to a VERY low blood sugar. In the animals’ body it acts similar to insulin which will lower the blood glucose. If glucose levels in the body get too low you can begin to see weakness, lethargy and even seizures. Depending on the amount the patient ingested signs can occur within 10 minutes to an hour. This is why immediate action is necessary.
 
A little bit goes a long way in our pets (Image Source)
Once the glucose is assessed and hopefully stabilized there is still another problem that can occur. This is liver failure and it very much depends on the amount of xylitol ingested. Once we know a pet has been exposed to xylitol we will recommend blood work to assess the glucose as well as get a baseline for the liver values. If glucose is low we will begin to supplement and get that stabilized.  Many times we will also begin to treat for possible liver disease. Depending on the dose ingested liver signs can start to show up within 9 hours or up to 72 hours. In some cases this can be severe and life threatening or lead to permanent liver damage.
 
While these products are safe for us they are NOT safe for our pets (Image Source)
Most of the time treatment will consist of glucose supplementation as needed until blood levels return to normal and also fluid therapy. Many times supplements like S-adensylmethionine, silymarin (milk thistle) and vitamin E and C will be added to help support the liver in its roll of filtering blood and scavenging for toxins.
 
Aggressive therapy is needed to help most patients (Image Source)

Treatment needs to be aggressive and early if a positive outcome is to be achieved. It is extremely important if you have pet to check the products you have around the house and if xylitol is in them either get rid of them, or keep them out of reach and temptation. For more information on xylitol toxicity please visit the following website

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